Moringa oleifera Lam. in Diabetes Mellitus: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis examined the effects of Moringa oleifera on diabetes mellitus by analyzing 18 studies with 641 total participants. Research suggests that moringa supplementation may help improve blood sugar control in people with diabetes. The analysis included both human clinical trials and animal studies that tested various moringa preparations, primarily leaf extracts and powders. Studies indicated significant improvements in fasting blood glucose levels, with some showing reductions of 20-30% compared to control groups. The review found that moringa may also help improve insulin sensitivity and reduce markers of diabetic complications. Most studies used moringa leaf preparations in doses ranging from 500mg to 8000mg daily for periods of 2-12 weeks. The authors noted that while results were generally positive across studies, there was considerable variation in study design, dosage, and duration. The meta-analysis suggests moringa could be a useful complementary approach for diabetes management, but emphasized the need for more standardized, long-term clinical trials to establish optimal dosing protocols and confirm safety profiles.