Muhammad Asif, Syed Ali Raza, Muhammad Kamran Khan et al.
Food Science & Nutrition (Wiley) • Apr 16, 2025
Mahdieh Abbasalizad Farhangi, Leila Nikniaz, Zeinab Nikniaz
Mahdieh Abbasalizad Farhangi, Leila Nikniaz, Zeinab Nikniaz (2025). Effects of Moringa oleifera leaf extract on glycemic control and inflammation in metabolic syndrome: a randomized controlled trial. ScienceDirect.
This randomized controlled trial investigated whether Moringa oleifera leaf extract could help manage blood sugar and inflammation in people with metabolic syndrome. Seventy-three Iranian adults with metabolic syndrome were randomly assigned to receive either 1000mg of moringa leaf extract twice daily or a placebo for 8 weeks. The study found significant improvements in key blood sugar markers among those taking moringa extract. Participants in the moringa group showed meaningful reductions in HbA1c levels, which reflects average blood sugar over 2-3 months, and improvements in insulin levels compared to the placebo group. These findings suggest that moringa leaf extract may help support healthy blood sugar management in people with metabolic syndrome. Metabolic syndrome is a cluster of conditions including high blood pressure, elevated blood sugar, excess abdominal fat, and abnormal cholesterol levels that increase the risk of heart disease and diabetes. The study adds to growing research indicating that moringa may have beneficial effects on glucose metabolism and could potentially serve as a complementary approach for managing metabolic health, though more research is needed to confirm long-term effects and optimal dosing.
Sample size
73 — metabolic syndrome patients
Duration
56 days
Plant part
Leaf
Preparation
Extract Other
Dosage
2000 mg (1000mg twice daily)
Country
Iran
2000mg daily total dose, administered as 1000mg twice daily, standardized leaf extract in capsule form, taken for 8 weeks
Muhammad Asif, Syed Ali Raza, Muhammad Kamran Khan et al.
Food Science & Nutrition (Wiley) • Apr 16, 2025
Silva M.A., Santos R.B., Oliveira C.D. et al.
Frontiers in Pharmacology • Apr 22, 2025
Morvaridzadeh M., Fazelian S., Agah S. et al.
Nutrients (MDPI) • Nov 7, 2025