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Efficacy and Safety of Moringa oleifera on Blood Glucose and Lipid Profile: A Meta-Analysis

Sirichai Adisakwattana, Thavaree Thilavech, Siriporn Chusak

Pharmacognosy Magazine1 January 2021
60
Moderate
Meta AnalysisPositiveBlood Sugar

Sirichai Adisakwattana, Thavaree Thilavech, Siriporn Chusak (2021). Efficacy and Safety of Moringa oleifera on Blood Glucose and Lipid Profile: A Meta-Analysis. Pharmacognosy Magazine.

This meta-analysis examined the effects of moringa leaf powder on blood sugar and cholesterol levels by combining results from 7 randomized controlled trials. Research suggests that moringa powder may help reduce fasting blood sugar and total cholesterol levels in people with normal to borderline cholesterol. The analysis found that treatment periods longer than 30 days were needed to see meaningful reductions in blood sugar levels. However, the studies showed no significant effects on LDL (bad) cholesterol, HDL (good) cholesterol, or triglycerides. The included studies used various dosages of moringa leaf powder and had relatively short treatment periods of less than 3 months. Most participants had normal or only slightly elevated cholesterol levels at the start of the studies. While the results suggest potential benefits for blood sugar and total cholesterol management, the researchers noted several limitations including the small number of available studies, short treatment durations, and the fact that participants generally had healthy cholesterol levels to begin with.

Study details

Sample size

7 — Meta-analysis including participants with normal to borderline cholesterol levels

Plant part

Leaf

Preparation

Powder

Dosage

Variable dosages across included studies

Country

Thailand

Dosage protocol

Variable dosages across included studies, moringa leaf powder form, treatment duration >30 days recommended for glucose effects

Key compounds

quercetinkaempferolchlorogenic acidisothiocyanatesniazimicin

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