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Exploring the dual benefits: acute and subacute toxicity, hypolipidemic, slimming and hypoglycemic effects of Moringa oleifera lam : Leaf extract in female wistar albino rats.

Kedaid H, Toumi I, Kraimat M, Adamou A, Mahamedi AE, Mezerai R, Telli A

Protoplasma14 March 2026
14
Exploratory
Animal In VivoPositiveBlood SugarNutritional Status

Kedaid H, Toumi I, Kraimat M et al. (2026). Exploring the dual benefits: acute and subacute toxicity, hypolipidemic, slimming and hypoglycemic effects of Moringa oleifera lam : Leaf extract in female wistar albino rats.. Protoplasma.

This animal study investigated the potential benefits and safety of Moringa oleifera leaf extract in female laboratory rats. Researchers examined whether the extract could help with blood sugar control, weight management, and cholesterol levels, while also testing for any toxic effects. The study looked at both immediate toxicity (acute) and longer-term safety (subacute) of the extract. Results suggest the moringa leaf extract may have beneficial effects on blood sugar levels, helping to lower them in a way that could be relevant for diabetes research. The extract also appeared to have hypolipidemic effects, meaning it may help reduce harmful fats and cholesterol in the blood. Additionally, the researchers found evidence of slimming or weight management effects. The toxicity testing suggested the extract was relatively safe at the doses tested, with no major harmful effects observed in either short-term or longer-term exposure. However, since this was conducted in laboratory rats, the findings cannot be directly applied to humans without further research. The study adds to the growing body of evidence suggesting moringa leaves may have multiple health benefits, particularly for metabolic health including blood sugar and lipid management.

Study details

Population

Female Wistar albino rats

Plant part

Leaf

Preparation

Extract Other

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