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Immunomodulatory and anticancer effects of moringa polyherbal infusions

Al-Rasheed N.M., Al-Otaibi M.M., Krychowiak M., Kfoury M., Fourmentin S., Greige-Gerges H.

Frontiers in Immunology5 June 2025
50
Preliminary
In VitroPositiveAnticancerImmune Function

Al-Rasheed N.M., Al-Otaibi M.M., Krychowiak M. et al. (2025). Immunomodulatory and anticancer effects of moringa polyherbal infusions. Frontiers in Immunology.

This laboratory study investigated the potential anticancer and immune-supporting effects of a polyherbal infusion combining moringa leaves with green tea and saffron against breast cancer cells. Researchers from Jordan and Saudi Arabia tested various concentrations of the aqueous extract on breast cancer cell lines to evaluate its ability to inhibit cancer cell growth and modulate immune responses. The study found that the moringa-containing polyherbal combination demonstrated significant antiproliferative effects, meaning it helped slow or stop the growth and multiplication of cancer cells. Additionally, the infusion showed immunomodulatory properties, suggesting it may help regulate immune system responses. The combination approach was designed to potentially enhance the individual benefits of each plant component through synergistic interactions. The aqueous extraction method mimics traditional tea preparation, making the findings more relevant to potential real-world applications. However, as an in vitro study using isolated cell lines, these results represent early-stage research that would require extensive further testing in animal models and human clinical trials before any therapeutic applications could be considered.

Study details

Population

In vitro (breast cancer cell line study)

Plant part

Leaf

Preparation

Extract Aqueous

Dosage

Polyherbal infusion combining moringa with green tea and saffron

Country

Jordan/Saudi Arabia

Dosage protocol

Polyherbal aqueous infusion, concentrations tested 50-500 μg/mL in vitro, optimal effects at 150-300 μg/mL range

Key compounds

isothiocyanatescatechinscrocinquercetinkaempferolchlorogenic acid

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