Moringa oleifera Lamk. as a Promising Adjunct Therapeutic Candidate: A Narrative Review of Human Studies and Published Case Reports

This narrative review examined 31 human studies and case reports investigating Moringa oleifera as a therapeutic intervention across various health conditions. The review analyzed studies involving patients with rheumatoid arthritis, diabetes, malnutrition, and dental conditions from multiple countries. Research suggests that moringa supplementation may support immune system restoration, help regulate blood sugar levels, and address nutritional deficiencies. In rheumatoid arthritis patients, studies indicated significant reductions in inflammatory markers, particularly IL-6 levels. Dental research showed that moringa-based treatments performed comparably to conventional sodium hypochlorite solutions. The reviewed studies generally reported minimal adverse effects, suggesting good tolerability across different populations. However, the dosages and preparation methods varied considerably between studies, making it difficult to establish standardized treatment protocols. The review highlights moringa's potential as an adjunct therapy but emphasizes the need for more rigorous clinical trials with standardized protocols to establish definitive therapeutic guidelines.